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Enzymatic synthesis of cyclic dinucleotide analogs by a promiscuous cyclic-AMP-GMP synthetase and analysis of cyclic dinucleotide responsive riboswitches

Cyclic dinucleotides are second messenger molecules produced by both prokaryotes and eukaryotes in response to external stimuli. In bacteria, these molecules bind to RNA riboswitches and several protein receptors ultimately leading to phenotypic changes such as biofilm formation, ion transport and s...

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Publicat a:Nucleic Acids Res
Autors principals: Launer-Felty, Katherine D, Strobel, Scott A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888326/
https://ncbi.nlm.nih.gov/pubmed/29514227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky137
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