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Diastolic dysfunction in pulmonary artery hypertension: Creatine kinase and the potential therapeutic benefit of beta‐blockers

Passive properties of the myocardium influence diastolic filling and cardiac output. In heart failure, changes in contributors to the passive properties of the ventricle, such as titin and collagen, and loss of the metabolic enzyme creatine kinase, increase resistance to filling resulting in diastol...

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Detalhes bibliográficos
Publicado no:Clin Exp Pharmacol Physiol
Main Authors: Fowler, Ewan D, Drinkhill, Mark J, Stones, Rachel, White, Ed
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887930/
https://ncbi.nlm.nih.gov/pubmed/29193283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12898
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