T cell receptor alpha variable 12‐2 bias in the immunodominant response to Yellow fever virus

The repertoire of human αβ T‐cell receptors (TCRs) is generated via somatic recombination of germline gene segments. Despite this enormous variation, certain epitopes can be immunodominant, associated with high frequencies of antigen‐specific T cells and/or exhibit bias toward a TCR gene segment. He...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Bovay, Amandine, Zoete, Vincent, Dolton, Garry, Bulek, Anna M., Cole, David K., Rizkallah, Pierre J., Fuller, Anna, Beck, Konrad, Michielin, Olivier, Speiser, Daniel E., Sewell, Andrew K., Fuertes Marraco, Silvia A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Adaptive immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887915/
https://ncbi.nlm.nih.gov/pubmed/28975614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747082
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