Hepatocyte‐induced CD4(+) T cell alloresponse is associated with major histocompatibility complex class II up‐regulation on hepatocytes and suppressible by regulatory T cells

Hepatocyte transplantation is a promising therapeutic approach for various liver diseases. Despite the liver's tolerogenic potential, early immune‐mediated loss of transplanted cells is observed, and longterm acceptance has not been achieved yet. Patients deemed tolerant after liver transplanta...

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Vydáno v:Liver Transpl
Hlavní autoři: DeTemple, Daphne E., Oldhafer, Felix, Falk, Christine S., Chen‐Wacker, Chen, Figueiredo, Constanca, Kleine, Moritz, Ramackers, Wolf, Timrott, Kai, Lehner, Frank, Klempnauer, Juergen, Bock, Michael, Vondran, Florian W. R.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887891/
https://ncbi.nlm.nih.gov/pubmed/29365365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.25019
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