S193. EX VIVO SIGNATURE OF PSYCHOSIS AND TREATMENT RESPONSE IN PATIENT-DERIVED NEURONS

BACKGROUND: Postmortem studies in schizophrenia show well-replicated neuronal differences in the prefrontal cortex (PFC), specifically showing lower dendritic spine density in upper-layer cortical pyramidal neurons. Animal models that recapitulate features of psychosis also show lower dendritic spin...

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Bibliographic Details
Published in:Schizophr Bull
Main Authors: Karmacharya, Rakesh, Watmuff, Bradley, Kathuria, Annie, Liu, Bangyan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887660/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sby018.980
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