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Measuring DNA hybridization using fluorescent DNA-stabilized silver clusters to investigate mismatch effects on therapeutic oligonucleotides

BACKGROUND: Short nucleic acid oligomers have found a wide range of applications in experimental physics, biology and medicine, and show potential for the treatment of acquired and genetic diseases. These applications rely heavily on the predictability of hybridization through Watson–Crick base pair...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: de Bruin, Donny, Bossert, Nelli, Aartsma-Rus, Annemieke, Bouwmeester, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887185/
https://ncbi.nlm.nih.gov/pubmed/29622040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0361-2
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