Mechanical barriers and transforming growth factor beta inhibitor on epidural fibrosis in a rabbit laminectomy model

BACKGROUND: TGF-β has been described as a mediator of fibrosis and scarring. Several studies achieved reduction in experimental scarring through the inhibition of TGF-β. Fibroblasts have been defined as the cell population originating fibrosis, blocking fibroblast invasion may impair epidural fibros...

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Библиографические подробности
Опубликовано в: :J Orthop Surg Res
Главные авторы: Albiñana-Cunningham, Juan N., Ripalda-Cemboráin, Purificación, Labiano, Tania, Echeveste, José I., Granero-Moltó, Froilán, Alfonso-Olmos, Matías
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887182/
https://ncbi.nlm.nih.gov/pubmed/29622010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-018-0781-6
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