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A Reassessment of Genes Modulating Aging in Mice Using Demographic Measurements of the Rate of Aging

Many studies have reported genetic interventions that have an effect on mouse life span; however, it is crucial to discriminate between manipulations of aging and aging-independent causes of life extension. Here, we used the Gompertz equation to determine whether previously reported aging-related mo...

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Dettagli Bibliografici
Pubblicato in:Genetics
Autori principali: Pedro de Magalhães, João, Thompson, Louise, de Lima, Izabella, Gaskill, Dale, Li, Xiaoyu, Thornton, Daniel, Yang, Chenhao, Palmer, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887152/
https://ncbi.nlm.nih.gov/pubmed/29444805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300821
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