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Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio

Genome-wide association studies (GWAS) have identified thousands of loci that are robustly associated with complex diseases. The use of linear mixed model (LMM) methodology for GWAS is becoming more prevalent due to its ability to control for population structure and cryptic relatedness and to incre...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Lloyd-Jones, Luke R., Robinson, Matthew R., Yang, Jian, Visscher, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887138/
https://ncbi.nlm.nih.gov/pubmed/29429966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300360
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