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The impact of cellular metabolism on chromatin dynamics and epigenetics

The substrates used to modify nucleic acids and chromatin are affected by nutrient availability and the activity of metabolic pathways. Thus, cellular metabolism constitutes a fundamental component of chromatin status and thereby of genome regulation. Here we describe the biochemical and genetic pri...

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Bibliographic Details
Published in:Nat Cell Biol
Main Authors: Reid, Michael A., Dai, Ziwei, Locasale, Jason W.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886854/
https://ncbi.nlm.nih.gov/pubmed/29058720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3629
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