Reduced Expression of Epidermal Growth Factor Receptors in Rat Liver During Aging

Proliferative responsiveness of hepatocytes to epidermal growth factor (EGF) declines during aging. The role of EGF receptors in mediating age-dependent changes of EGF-induced mitogenic signaling in liver remains incompletely understood. We assessed EGF receptor expression levels in whole liver spec...

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Veröffentlicht in:J Gerontol A Biol Sci Med Sci
Hauptverfasser: Kamat, Amrita, Ghosh, Paramita M., Glover, Renee L., Zhu, Bing, Yeh, Chih-Ko, Ghosh Choudhury, Goutam, Katz, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886784/
https://ncbi.nlm.nih.gov/pubmed/18693222
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