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Lineage-biased hematopoietic stem cells are regulated by distinct niches

The spatial localization of hematopoietic stem cells (HSCs) in the bone marrow (BM) remains controversial with studies suggesting that they are maintained in homogenously distributed niches while others have suggested the contributions of distinct niche structures. Subsets of quiescent HSCs have bee...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Pinho, Sandra, Marchand, Tony, Yang, Eva, Wei, Qiaozhi, Nerlov, Claus, Frenette, Paul S.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886750/
https://ncbi.nlm.nih.gov/pubmed/29456137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.01.016
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