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Replicated linear association between DUF1220 copy number and severity of social impairment in autism

Sequences encoding DUF1220 protein domains exhibit an exceptional human-specific increase in copy number and have been associated with several phenotypes related to brain size. Autism is a highly heritable and heterogeneous condition characterized behaviorally by social and communicative impairments...

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Bibliografiske detaljer
Udgivet i:Hum Genet
Main Authors: Davis, JM, Quick, VB Searles, Sikela, JM
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886748/
https://ncbi.nlm.nih.gov/pubmed/25758905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-015-1537-6
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