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Oxygen-sensing neurons reciprocally regulate peripheral lipid metabolism via neuropeptide signaling in Caenorhabditis elegans

The mechanisms by which the sensory environment influences metabolic homeostasis remains poorly understood. In this report, we show that oxygen, a potent environmental signal, is an important regulator of whole body lipid metabolism. C. elegans oxygen-sensing neurons reciprocally regulate peripheral...

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Vydáno v:PLoS Genet
Hlavní autoři: Hussey, Rosalind, Littlejohn, Nicole K., Witham, Emily, Vanstrum, Erik, Mesgarzadeh, Jaleh, Ratanpal, Harkaranveer, Srinivasan, Supriya
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886693/
https://ncbi.nlm.nih.gov/pubmed/29579048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007305
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