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DNA strand-exchange patterns associated with double-strand break-induced and spontaneous mitotic crossovers in Saccharomyces cerevisiae

Mitotic recombination can result in loss of heterozygosity and chromosomal rearrangements that shape genome structure and initiate human disease. Engineered double-strand breaks (DSBs) are a potent initiator of recombination, but whether spontaneous events initiate with the breakage of one or both D...

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Publicat a:PLoS Genet
Autors principals: Hum, Yee Fang, Jinks-Robertson, Sue
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886692/
https://ncbi.nlm.nih.gov/pubmed/29579095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007302
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