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Optic neuropathies: the tip of the neurodegeneration iceberg

The optic nerve and the cells that give origin to its 1.2 million axons, the retinal ganglion cells (RGCs), are particularly vulnerable to neurodegeneration related to mitochondrial dysfunction. Optic neuropathies may range from non-syndromic genetic entities, to rare syndromic multisystem diseases...

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Dades bibliogràfiques
Publicat a:Hum Mol Genet
Autors principals: Carelli, Valerio, La Morgia, Chiara, Ross-Cisneros, Fred N., Sadun, Alfredo A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886475/
https://ncbi.nlm.nih.gov/pubmed/28977448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx273
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