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From compliment to insult: genetics of the complement system in physiology and disease in the human retina

Age-related macular degeneration (AMD) is a major cause of visual impairment that affects the central retina. Genome wide association studies and candidate gene screens have identified members of the complement pathway as contributing to the risk of AMD. In this review, we discuss the complement sys...

Ausführliche Beschreibung

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Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Mullins, Robert F., Warwick, Alasdair N., Sohn, Elliott H., Lotery, Andrew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886463/
https://ncbi.nlm.nih.gov/pubmed/28482029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx181
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