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Molecular evolution of DNMT1 in vertebrates: Duplications in marsupials followed by positive selection

DNA methylation is mediated by a conserved family of DNA methyltransferases (Dnmts). The human genome encodes three active Dnmts (Dnmt1, Dnmt3a and Dnmt3b), the tRNA methyltransferase Dnmt2, and the regulatory protein Dnmt3L. Despite their high degree of conservation among different species, genes e...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Alvarez-Ponce, David, Torres-Sánchez, María, Feyertag, Felix, Kulkarni, Asmita, Nappi, Taylen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886458/
https://ncbi.nlm.nih.gov/pubmed/29621315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195162
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