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Mouse Models for Drug Discovery. Can New Tools and Technology Improve Translational Power?

The use of mouse models in biomedical research and preclinical drug evaluation is on the rise. The advent of new molecular genome-altering technologies such as CRISPR/Cas9 allows for genetic mutations to be introduced into the germ line of a mouse faster and less expensively than previous methods. I...

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Detalhes bibliográficos
Publicado no:ILAR J
Main Authors: Zuberi, Aamir, Lutz, Cathleen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886322/
https://ncbi.nlm.nih.gov/pubmed/28053071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ilar/ilw021
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