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Mouse Models for Drug Discovery. Can New Tools and Technology Improve Translational Power?

The use of mouse models in biomedical research and preclinical drug evaluation is on the rise. The advent of new molecular genome-altering technologies such as CRISPR/Cas9 allows for genetic mutations to be introduced into the germ line of a mouse faster and less expensively than previous methods. I...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ILAR J
Prif Awduron: Zuberi, Aamir, Lutz, Cathleen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886322/
https://ncbi.nlm.nih.gov/pubmed/28053071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ilar/ilw021
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