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Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal

It is clear that innate immune system status is altered in numerous neurodegenerative diseases. Human genetic studies have demonstrated that triggering receptor expressed in myeloid cells 2 (TREM2) coding variants have a strong association with Alzheimer’s disease (AD) and other neurodegenerative di...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Kang, Silvia S, Kurti, Aishe, Baker, Kelsey E, Liu, Chia-Chen, Colonna, Marco, Ulrich, Jason D, Holtzman, David M, Bu, Guojun, Fryer, John D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886290/
https://ncbi.nlm.nih.gov/pubmed/29040522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx366
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