טוען...
A human patient-derived cellular model of Joubert syndrome reveals ciliary defects which can be rescued with targeted therapies
Joubert syndrome (JBTS) is the archetypal ciliopathy caused by mutation of genes encoding ciliary proteins leading to multi-system phenotypes, including a cerebello-retinal-renal syndrome. JBTS is genetically heterogeneous, however mutations in CEP290 are a common underlying cause. The renal manifes...
שמור ב:
| הוצא לאור ב: | Hum Mol Genet |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5886250/ https://ncbi.nlm.nih.gov/pubmed/28973549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx347 |
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