DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis

DJ-1 is an oxidation sensitive protein encoded by the PARK7 gene. Mutations in PARK7 are a rare cause of familial recessive Parkinson’s disease (PD), but growing evidence suggests involvement of DJ-1 in idiopathic PD. The key clinical features of PD, rigidity and bradykinesia, result from neurotrans...

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Publicado no:Hum Mol Genet
Main Authors: Piston, Dominik, Alvarez-Erviti, Lydia, Bansal, Vikas, Gargano, Daniela, Yao, Zhi, Szabadkai, Gyorgy, Odell, Mark, Puno, M Rhyan, Björkblom, Benny, Maple-Grødem, Jodi, Breuer, Peter, Kaut, Oliver, Larsen, Jan Petter, Bonn, Stefan, Møller, Simon Geir, Wüllner, Ullrich, Schapira, Anthony H V, Gegg, Matthew E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886150/
https://ncbi.nlm.nih.gov/pubmed/29016861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx294
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