Clinical outcome of concomitant vs interrupted BRAF inhibitor therapy during radiotherapy in melanoma patients

BACKGROUND: Concomitant radiation with BRAF inhibitor (BRAFi) therapy may increase radiation-induced side effects but also potentially improve tumour control in melanoma patients. METHODS: A total of 155 patients with BRAF-mutated melanoma from 17 European skin cancer centres were retrospectively an...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Hecht, Markus, Meier, Friedegund, Zimmer, Lisa, Polat, Bülent, Loquai, Carmen, Weishaupt, Carsten, Forschner, Andrea, Gutzmer, Ralf, Utikal, Jochen S, Goldinger, Simone M, Geier, Michael, Hassel, Jessica C, Balermpas, Panagiotis, Kiecker, Felix, Rauschenberg, Ricarda, Dietrich, Ursula, Clemens, Patrick, Berking, Carola, Grabenbauer, Gerhard, Schadendorf, Dirk, Grabbe, Stephan, Schuler, Gerold, Fietkau, Rainer, Distel, Luitpold V, Heinzerling, Lucie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886123/
https://ncbi.nlm.nih.gov/pubmed/29438368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.489
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