The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice

A number of mutations in genes that encode ubiquitously expressed RNA-binding proteins cause tissue specific disease. Many of these diseases are neurological in nature revealing critical roles for this class of proteins in the brain. We recently identified mutations in a gene that encodes a ubiquito...

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Pubblicato in:Hum Mol Genet
Autori principali: Rha, Jennifer, Jones, Stephanie K., Fidler, Jonathan, Banerjee, Ayan, Leung, Sara W., Morris, Kevin J., Wong, Jennifer C., Inglis, George Andrew S., Shapiro, Lindsey, Deng, Qiudong, Cutler, Alicia A., Hanif, Adam M., Pardue, Machelle T., Schaffer, Ashleigh, Seyfried, Nicholas T., Moberg, Kenneth H., Bassell, Gary J., Escayg, Andrew, García, Paul S., Corbett, Anita H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886104/
https://ncbi.nlm.nih.gov/pubmed/28666327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx248
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