Effect of On-Demand vs Routine Nebulization of Acetylcysteine With Salbutamol on Ventilator-Free Days in Intensive Care Unit Patients Receiving Invasive Ventilation: A Randomized Clinical Trial

IMPORTANCE: It remains uncertain whether nebulization of mucolytics with bronchodilators should be applied for clinical indication or preventively in intensive care unit (ICU) patients receiving invasive ventilation. OBJECTIVE: To determine if a strategy that uses nebulization for clinical indicatio...

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Publicado en:JAMA
Autores principales: van Meenen, David M. P., van der Hoeven, Sophia M., Binnekade, Jan M., de Borgie, Corianne A. J. M., Merkus, Maruschka P., Bosch, Frank H., Endeman, Henrik, Haringman, Jasper J., van der Meer, Nardo J. M., Moeniralam, Hazra S., Slabbekoorn, Mathilde, Muller, Marcella C. A., Stilma, Willemke, van Silfhout, Bart, Neto, Ary Serpa, ter Haar, Hans F. M., Van Vliet, Jan, Wijnhoven, Jan Willem, Horn, Janneke, Juffermans, Nicole P., Pelosi, Paolo, Gama de Abreu, Marcelo, Schultz, Marcus J., Paulus, Frederique
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2018
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885882/
https://ncbi.nlm.nih.gov/pubmed/29486489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.0949
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