Effect of On-Demand vs Routine Nebulization of Acetylcysteine With Salbutamol on Ventilator-Free Days in Intensive Care Unit Patients Receiving Invasive Ventilation: A Randomized Clinical Trial

IMPORTANCE: It remains uncertain whether nebulization of mucolytics with bronchodilators should be applied for clinical indication or preventively in intensive care unit (ICU) patients receiving invasive ventilation. OBJECTIVE: To determine if a strategy that uses nebulization for clinical indicatio...

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Bibliografske podrobnosti
izdano v:JAMA
Main Authors: van Meenen, David M. P., van der Hoeven, Sophia M., Binnekade, Jan M., de Borgie, Corianne A. J. M., Merkus, Maruschka P., Bosch, Frank H., Endeman, Henrik, Haringman, Jasper J., van der Meer, Nardo J. M., Moeniralam, Hazra S., Slabbekoorn, Mathilde, Muller, Marcella C. A., Stilma, Willemke, van Silfhout, Bart, Neto, Ary Serpa, ter Haar, Hans F. M., Van Vliet, Jan, Wijnhoven, Jan Willem, Horn, Janneke, Juffermans, Nicole P., Pelosi, Paolo, Gama de Abreu, Marcelo, Schultz, Marcus J., Paulus, Frederique
Format: Artigo
Jezik:Inglês
Izdano: American Medical Association 2018
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885882/
https://ncbi.nlm.nih.gov/pubmed/29486489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.0949
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