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Efficacy and Safety of Guselkumab, an Anti–interleukin 23 Monoclonal Antibody, for Palmoplantar Pustulosis: A Randomized Clinical Trial

IMPORTANCE: Palmoplantar pustulosis (PPP) is a recalcitrant skin disease with no biologics currently approved for treatment. The involvement of interleukin 23 (IL-23) and cytokines of the type 17 helper T cell lineage in the pathogenesis of PPP has been recently postulated. OBJECTIVE: To evaluate th...

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Detalhes bibliográficos
Publicado no:JAMA Dermatol
Main Authors: Terui, Tadashi, Kobayashi, Satomi, Okubo, Yukari, Murakami, Masamoto, Hirose, Keiichiro, Kubo, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885837/
https://ncbi.nlm.nih.gov/pubmed/29417135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamadermatol.2017.5937
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