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DNA Methylation in Osteoarthritis: Current Status and Therapeutic Implications

BACKGROUND: Primary Osteoarthritis (OA) is a multifactorial disease in which genetic factors are strongly associated with its development; however, recently it has been observed that epigenetic modifications are also involved in the pathogenesis of OA. DNA methylation is related to gene silencing, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Open Rheumatol J
1. Verfasser: Miranda-Duarte, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Open 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885469/
https://ncbi.nlm.nih.gov/pubmed/29682093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874312901812010037
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