Cathepsin K associates with lymph node metastasis and poor prognosis in oral squamous cell carcinoma

BACKGROUND: Lymph node metastasis (LNM) is a major determinant of prognosis and treatment planning of oral squamous cell carcinoma (OSCC). Cysteine cathepsins constitute a family of proteolytic enzymes with known role in the degradation of the extracellular matrix. Involvement in pathological proces...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Leusink, Frank K., Koudounarakis, Eleftherios, Frank, Michael H., Koole, Ronald, van Diest, Paul J., Willems, Stefan M.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885370/
https://ncbi.nlm.nih.gov/pubmed/29618339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4315-8
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