Efficacy of PD-1 & PD-L1 inhibitors in older adults: a meta-analysis

BACKGROUND: Immune checkpoint inhibitors targeting PD-1/PD-L1 pathway demonstrated promising activities in variety of malignancies, however little is known regarding their efficacy in adults aged ≥65 years. METHODS: We conducted a systematic review and a study-level meta-analysis to explore efficacy...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Immunother Cancer
Main Authors: Elias, Rawad, Giobbie-Hurder, Anita, McCleary, Nadine Jackson, Ott, Patrick, Hodi, F. Stephen, Rahma, Osama
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885356/
https://ncbi.nlm.nih.gov/pubmed/29618381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0336-8
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