Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma: The EORTC 62961-ESHO 95 Randomized Clinical Trial

IMPORTANCE: Patients with soft tissue sarcoma are at risk for local recurrence and distant metastases despite optimal local treatment. Preoperative anthracycline plus ifosfamide chemotherapy improves outcome in common histological subtypes. OBJECTIVE: To analyze whether the previously reported impro...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Issels, Rolf D., Lindner, Lars H., Verweij, Jaap, Wessalowski, Rüdiger, Reichardt, Peter, Wust, Peter, Ghadjar, Pirus, Hohenberger, Peter, Angele, Martin, Salat, Christoph, Vujaskovic, Zeljko, Daugaard, Soeren, Mella, Olav, Mansmann, Ulrich, Dürr, Hans Roland, Knösel, Thomas, Abdel-Rahman, Sultan, Schmidt, Michael, Hiddemann, Wolfgang, Jauch, Karl-Walter, Belka, Claus, Gronchi, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885262/
https://ncbi.nlm.nih.gov/pubmed/29450452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.4996
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