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Efficacy and Safety of First-line Avelumab Treatment in Patients With Stage IV Metastatic Merkel Cell Carcinoma: A Preplanned Interim Analysis of a Clinical Trial

IMPORTANCE: Merkel cell carcinoma (MCC) is an aggressive skin cancer that is associated with poor survival outcomes in patients with distant metastatic disease. Results of part A of the JAVELIN Merkel 200 trial (avelumab in patients with Merkel cell carcinoma) showed that avelumab, an anti–programme...

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Publicat a:JAMA Oncol
Autors principals: D’Angelo, Sandra P., Russell, Jeffery, Lebbé, Céleste, Chmielowski, Bartosz, Gambichler, Thilo, Grob, Jean-Jacques, Kiecker, Felix, Rabinowits, Guilherme, Terheyden, Patrick, Zwiener, Isabella, Bajars, Marcis, Hennessy, Meliessa, Kaufman, Howard L.
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885245/
https://ncbi.nlm.nih.gov/pubmed/29566106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.0077
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