Association of Cerebrospinal Fluid Biomarkers of Central Nervous System Injury With Neurocognitive and Brain Imaging Outcomes in Children Receiving Chemotherapy for Acute Lymphoblastic Leukemia

IMPORTANCE: Little is known about treatment-related neurotoxic mechanisms in children with acute lymphoblastic leukemia (ALL) treated with chemotherapy only. OBJECTIVE: To examine concentration of cerebrospinal fluid (CSF) biomarkers of brain injury at ALL diagnosis and during cancer therapy and to...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Cheung, Yin Ting, Khan, Raja B., Liu, Wei, Brinkman, Tara M., Edelmann, Michelle N., Reddick, Wilburn E., Pei, Deqing, Panoskaltsis-Mortari, Angela, Srivastava, Deokumar, Cheng, Cheng, Robison, Leslie L., Hudson, Melissa M., Pui, Ching-Hon, Krull, Kevin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885182/
https://ncbi.nlm.nih.gov/pubmed/29596541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.0089
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