Comparative 'omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

Members of the Mycobacterium tuberculosis complex (MTBC) are the causative agents of tuberculosis in a range of mammals, including humans. A key feature of MTBC pathogens is their high degree of genetic identity yet distinct host tropism. Notably, while Mycobacterium bovis is highly virulent and pat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Microb Genom
Main Authors: Malone, Kerri M., Rue-Albrecht, Kévin, Magee, David A., Conlon, Kevin, Schubert, Olga T., Nalpas, Nicolas C., Browne, John A., Smyth, Alicia, Gormley, Eamonn, Aebersold, Ruedi, MacHugh, David E., Gordon, Stephen V.
Format: Artigo
Jezik:Inglês
Izdano: Microbiology Society 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885015/
https://ncbi.nlm.nih.gov/pubmed/29557774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mgen.0.000163
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