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Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals

In humans the expression of lactase changes during post-natal development, leading to phenotypes known as lactase persistence and non-persistence. Polymorphisms within the lactase gene (LCT) enhancer, in particular the −13910C > T, but also others, are linked to these phenotypes. We were interest...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leseva, Milena N., Grand, Richard J., Klett, Hagen, Boerries, Melanie, Busch, Hauke, Binder, Alexandra M., Michels, Karin B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884863/
https://ncbi.nlm.nih.gov/pubmed/29618745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23957-4
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