Discriminating MGMT Promoter Methylation Status in Patients with Glioblastoma Employing Amide Proton Transfer-Weighted MRI Metrics

OBJECTIVES: To explore the feasibility of using amide proton transfer-weighted (APTw) MRI metrics as surrogate biomarkers to identify the O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation status in glioblastoma (GBM). METHODS: Eighteen newly diagnosed GBM patients, who were previous...

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Detalhes bibliográficos
Publicado no:Eur Radiol
Main Authors: Jiang, Shanshan, Rui, Qihong, Wang, Yu, Heo, Hye-Young, Zou, Tianyu, Yu, Hao, Zhang, Yi, Wang, Xianlong, Du, Yongxing, Wen, Xinrui, Chen, Fangyao, Wang, Jihong, Eberhart, Charles G., Zhou, Jinyuan, Wen, Zhibo
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884703/
https://ncbi.nlm.nih.gov/pubmed/29234914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00330-017-5182-4
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