The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma

The lncRNA HOTAIR has been implicated in several human cancers. Here, we evaluated the molecular alterations and upstream regulatory mechanisms of HOTAIR in glioma, the most common primary brain tumors, and its clinical relevance. HOTAIR gene expression, methylation, copy-number and prognostic value...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Xavier-Magalhães, Ana, Gonçalves, Céline S., Fogli, Anne, Lourenço, Tatiana, Pojo, Marta, Pereira, Bruno, Rocha, Miguel, Lopes, Maria Celeste, Crespo, Inês, Rebelo, Olinda, Tão, Herminio, Lima, João, Moreira, Ricardo, Pinto, Afonso A., Jones, Chris, Reis, Rui M., Costello, Joseph F., Arnaud, Philippe, Sousa, Nuno, Costa, Bruno M.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2018
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884661/
https://ncbi.nlm.nih.gov/pubmed/29644006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24597
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