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The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

The still largely obscure molecular events in the glioblastoma oncogenesis, a primary brain tumor characterized by an inevitably dismal prognosis, impel for investigation. The importance of Long noncoding RNAs as regulators of gene expression has recently become evident. Among them, H19 has a recogn...

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Vydáno v:Oncotarget
Hlavní autoři: Fazi, Barbara, Garbo, Sabrina, Toschi, Nicola, Mangiola, Annunziato, Lombari, Malinska, Sicari, Daria, Battistelli, Cecilia, Galardi, Silvia, Michienzi, Alessandro, Trevisi, Gianluca, Harari-Steinfeld, Rona, Cicchini, Carla, Ciafrè, Silvia Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884644/
https://ncbi.nlm.nih.gov/pubmed/29643989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24496
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