The glucocorticoid receptor in recipient cells keeps cytokine secretion in acute graft-versus-host disease at bay

Graft-versus-host disease (GvHD) is a life-threatening complication of hematopoietic stem cell transplantation (HSCT), which is caused by allogeneic T cells recognizing molecules of the recipient as foreign. Endogenous glucocorticoids (GC) released from the adrenal gland are crucial in regulating su...

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Udgivet i:Oncotarget
Main Authors: Baake, Tina, Jörß, Katharina, Suennemann, Jennifer, Roßmann, Laura, Bohnenberger, Hanibal, Tuckermann, Jan P., Reichardt, Holger M., Fischer, Henrike J., Reichardt, Sybille D.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper: Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884639/
https://ncbi.nlm.nih.gov/pubmed/29643984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24602
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