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Tissue Inhibitor of Metalloproteinase–3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells

Over expression of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) in vascular smooth muscle cells (VSMCs) induces apoptosis and reduces neointima formation occurring after saphenous vein interposition grafting or coronary stenting. In studies to address the mechanism of TIMP-3-driven apoptosis in...

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Publié dans:PLoS One
Auteurs principaux: English, William R., Ireland-Zecchini, Heather, Baker, Andrew H., Littlewood, Trevor D., Bennett, Martin R., Murphy, Gillian
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884528/
https://ncbi.nlm.nih.gov/pubmed/29617412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195116
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