Celecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy

Autosomal dominant lateral temporal epilepsy (ADLTE) is an inherited syndrome caused by mutations in the leucine-rich glioma inactivated 1 (LGI1) gene. It is known that glutamatergic transmission is altered in LGI1 mutant mice, and seizures can be reduced by restoring LGI1 function. Yet, the mechani...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhou, Lin, Zhou, Liang, Su, Li-da, Cao, Sheng-Long, Xie, Ya-Jun, Wang, Na, Shao, Chong-Yu, Wang, Ya-Nan, Zhou, Jia-Huan, Cowell, John K., Shen, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884462/
https://ncbi.nlm.nih.gov/pubmed/29491011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3245-17.2018
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