Dose-Dependent Relationship Between Metformin and Colorectal Cancer Occurrence Among Patients with Type 2 Diabetes—A Nationwide Cohort Study()()()

BACKGROUND: Increasing bodies of evidence suggest that metformin may be beneficial in the primary prevention of colorectal cancer (CRC), and a dose–response relationship has been reported. However, long-term epidemiological observations between the treatment period, cumulative dose, and intensity of...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Chang, Yu-Tang, Tsai, Hsiang-Lin, Kung, Ya-Ting, Yeh, Yung-Sung, Huang, Ching-Wen, Ma, Cheng-Jen, Chiu, Herng-Chia, Wang, Jaw-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884217/
https://ncbi.nlm.nih.gov/pubmed/29524831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.02.012
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