Tumstatin, a Matrikine Derived from Collagen Type IVα3, is Elevated in Serum from Patients with Non–Small Cell Lung Cancer

OBJECTIVES: Fibrosis and cancer are characterized by extracellular matrix (ECM) remodeling. The basement membrane is mainly composed by collagen type IV and laminin. Tumstatin is a matrix metalloproteinase-9 (MMP-9) generated matrikine of collagen type IV α3 chain. We evaluated the potential of tums...

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Publicat a:Transl Oncol
Autors principals: Nielsen, Signe Holm, Willumsen, Nicholas, Brix, Susanne, Sun, Shu, Manon-Jensen, Tina, Karsdal, Morten, Genovese, Federica
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2018
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884192/
https://ncbi.nlm.nih.gov/pubmed/29524830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.02.005
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