Mutational Profiling of Malignant Mesothelioma Revealed Potential Therapeutic Targets in EGFR and NRAS

Pemetrexed and platinum (PP) combination chemotherapy is the current standard first-line therapy for treatment of malignant mesothelioma (MM). However, a useful predictive biomarker for PP therapy is yet to be found. Here, we performed targeted exome sequencing to profile somatic mutations and copy...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Kim, Jeong Eun, Kim, Deokhoon, Hong, Yong Sang, Kim, Kyu-pyo, Yoon, Young Kwang, Lee, Dae Ho, Kim, Sang-We, Chun, Sung-Min, Jang, Se Jin, Kim, Tae Won
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884183/
https://ncbi.nlm.nih.gov/pubmed/29413759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.01.005
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