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A T cell equation as a conceptual model of T cell responses for maximizing the efficacy of cancer immunotherapy

Following antigen stimulation, the net outcomes of a T cell response are shaped by integrated signals from both positive co-stimulatory and negative regulatory molecules. Recently, the blockade of negative regulatory molecules (i.e. immune checkpoint signals) demonstrates promising therapeutic effec...

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Detalhes bibliográficos
Publicado no:SOJ Immunol
Main Authors: Dong, Haidong, Yan, Yiyi, Dronca, Roxana S., Markovic, Svetomir N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884168/
https://ncbi.nlm.nih.gov/pubmed/29629436
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