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The anti-nociceptive agent SBFI-26 binds to anandamide transporters FABP5 and FABP7 at two different sites
Human FABP5 and FABP7 are intracellular endocannabinoid transporters. SBFI-26 is an α-truxillic acid 1-naphthyl monoester that inhibits the activities of FABP5 and FABP7 and produces antinociceptive and anti-inflammatory effects in mice. The synthesis of SBFI-26 yields several stereoisomers, and it...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5884075/ https://ncbi.nlm.nih.gov/pubmed/28632393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00194 |
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