Localized Delivery of Cl-Amidine From Electrospun Polydioxanone Templates to Regulate Acute Neutrophil NETosis: A Preliminary Evaluation of the PAD4 Inhibitor for Tissue Engineering

Upon interaction, neutrophils can potentially release neutrophil extracellular traps (NETs) on the surface of an implanted electrospun template, which may be a significant preconditioning event for implantable biomaterials of yet unknown consequences. In this study, we investigated the potential of...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Fetz, Allison E., Neeli, Indira, Buddington, Karyl K., Read, Robert W., Smeltzer, Matthew P., Radic, Marko Z., Bowlin, Gary L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883633/
https://ncbi.nlm.nih.gov/pubmed/29643810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00289
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