Human CCL3L1 copy number variation, gene expression, and the role of the CCL3L1-CCR5 axis in lung function

Background: The CCL3L1-CCR5 signaling axis is important in a number of inflammatory responses, including macrophage function, and T-cell-dependent immune responses. Small molecule CCR5 antagonists exist, including the approved antiretroviral drug maraviroc, and therapeutic monoclonal antibodies are...

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Detalhes bibliográficos
Publicado no:Wellcome Open Res
Main Authors: Adewoye, Adeolu B., Shrine, Nick, Odenthal-Hesse, Linda, Welsh, Samantha, Malarstig, Anders, Jelinsky, Scott, Kilty, Iain, Tobin, Martin D., Hollox, Edward J., Wain, Louise V.
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883389/
https://ncbi.nlm.nih.gov/pubmed/29682616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.13902.2
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