Prediction of treatment responses to neoadjuvant chemotherapy in triple-negative breast cancer by analysis of immune checkpoint protein expression

BACKGROUND: “Avoiding immune destruction” has recently been established as one of the hallmarks of cancer. The programmed cell death (PD)-1/programmed cell death-ligand (PD-L) 1 pathway is an important immunosuppression mechanism that allows cancer cells to escape host immunity. The present study in...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Asano, Yuka, Kashiwagi, Shinichiro, Goto, Wataru, Takada, Koji, Takahashi, Katsuyuki, Morisaki, Tamami, Fujita, Hisakazu, Takashima, Tsutomu, Tomita, Shuhei, Ohsawa, Masahiko, Hirakawa, Kosei, Ohira, Masaichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883348/
https://ncbi.nlm.nih.gov/pubmed/29615063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1458-y
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