Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is persistently activated in a wide variety of epithelial cancers. Aberrant activity of STAT3 correlates with tumor growth, invasion and metastasis, which makes it a potential therapeutic target of cancer. To explore the biologic...

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Publicat a:Cancer Cell Int
Autors principals: Zhou, Chao, Ma, Jie, Su, Mengyuan, Shao, Dan, Zhao, Jianan, Zhao, Tongjian, Song, Zhuoyao, Meng, Yan, Jiao, Ping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883295/
https://ncbi.nlm.nih.gov/pubmed/29636641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0549-4
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