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MiR-544 promotes immune escape through downregulation of NCR1/NKp46 via targeting RUNX3 in liver cancer

OBJECTIVE: To study the potential role of miR-544 in the immune escape mechanism of hepatoma cells. METHODS: Natural killer (NK) cells were collected from healthy volunteers and patients with liver cancer. Interleukin (IL)-2 activated-NK-92 cells were transfected with miR-544 inhibitor/mimic or NC/p...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Pan, Chenwei, Xiang, Luxia, Pan, Zhenzhen, Wang, Xiaodong, Li, Jie, Zhuge, Lu, Fang, Peipei, Xie, Qipeng, Hu, Xuezhen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883289/
https://ncbi.nlm.nih.gov/pubmed/29636640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0542-y
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